Evaluating survival in subjects with astrocytic brain tumors by dynamic susceptibility-weighted perfusion MR imaging

Dynamic susceptibility contrast-enhanced perfusion MR Imaging of Brain Tumors

Direct Comparison of Dynamic Susceptibility Weighted MR Perfusion with CT Perfusion in Brain Tumors

Introduction: Contrast Agents (CAs) are widely used as indicators to study quantitative perfusion and Blood Brain Barrier (BBB) permeability in MRI, and are useful in characterizing pathology [1]. A common assumption is that the relationship between longitudinal relaxation rate change and Gd concentration is linear. In general, this assumption depends on the size of the molecules to which the G...

Dynamic contrast-enhanced susceptibility-weighted perfusion imaging of intracranial tumors: a study using a 3T MR scanner.

PURPOSE To determine whether there are statistically significant differences in cerebral blood volume (CBV) and cerebral blood flow (CBF) of brain tumors of different histopathologic types including primary and secondary benign and malignant lesions. To determine whether these measurements relate to tumor grade. MATERIALS AND METHODS Forty-five patients with brain tumors, age 2 to 79 years, u...

Cerebral perfusion MR imaging using FAIR-HASTE in chronic carotid occlusive disease: comparison with dynamic susceptibility contrast-perfusion MR imaging.

To determine the efficacy of flow-sensitive alternating inversion recovery using half-Fourier single-shot turbo spin-echo (FAIR-HASTE) in detecting cerebral hypoperfusion in chronic carotid occlusive disease, we subjected 12 patients with various degrees of cervical internal carotid artery stenoses and/or occlusion (Stenosis group) and 24 volunteers (Normal group) to FAIR-HASTE. In addition, 10...

Differentiation between oligodendroglioma genotypes using dynamic susceptibility contrast perfusion-weighted imaging and proton MR spectroscopy.

BACKGROUND AND PURPOSE Oligodendrogliomas with 1p/19q chromosome LOH are more sensitive to chemoradiation therapy than those with intact alleles. The usefulness of dynamic susceptibility contrast-PWI-guided ¹H-MRS in differentiating these 2 genotypes was tested in this study. MATERIALS AND METHODS Forty patients with oligodendrogliomas, 1p/19q LOH (n = 23) and intact alleles (n = 17), underwe...